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第 56 卷第 4 期 李莹莹，等：丙酸钠缓解鼠柠檬酸杆菌诱导的小鼠结肠炎效果优于混合短链脂肪酸 497

and SCFAs production in rats with TNBS-induced colitis[J]. ry and antioxidant effects of sodium propionate[J]. Int J Mol
Food Res Int, 2022, 157: 111390. Sci, 2020, 21(8): 3026.
[7] Lee JG, Lee J, Lee AR, et al. Impact of short-chain fatty acid [22] Tarrerias AL, Millecamps M, Alloui A, et al. Short-chain fatty
supplementation on gut inflammation and microbiota composi- acid enemas fail to decrease colonic hypersensitivity and in-
tion in a murine colitis model[J]. J Nutr Biochem, 2022, 101: flammation in TNBS-induced colonic inflammation in rats[J].
108926. Pain, 2002, 100(1/2): 91-97.
[8] Wu YQ, Jha R, Li A, et al. Probiotics (Lactobacillus plantarum [23] Ji J, Shu DM, Zheng MZ, et al. Microbial metabolite butyrate
HNU082) supplementation relieves ulcerative colitis by affect- facilitates M2 macrophage polarization and function[J]. Sci Rep,
ing intestinal barrier functions, immunity-related gene expres- 2016, 6: 24838.
sion, gut microbiota, and metabolic pathways in mice[J]. Micro- [24] Araki Y, Andoh A, Takizawa J, et al. Clostridium butyricum, a
biol Spectr, 2022, 10(6): e0165122. probiotic derivative, suppresses dextran sulfate sodium-induced
[9] Feng YH, Huang YL, Wang P, et al. Effects of short chain fatty experimental colitis in rats[J]. Int J Mol Med, 2004, 13(4): 577-
acid on barrier disruption of human intestinal epithelial cell in- 580.
duced by endotoxin/lipopolysaccharide and the related mecha- [25] Shaker AS, Marrez DA, Ali MA, et al. Potential synergistic ef-
nism[J]. Chin J Burns(中华烧伤杂志), 2018, 34(4): 214-218. fect of Alhagi graecorum ethanolic extract with two convention-
[10] Mao TY, Su CW, Ji QR, et al. Hyaluronan-induced alterations al food preservatives against some foodborne pathogens[J].
of the gut microbiome protects mice against Citrobacter roden- Arch Microbiol, 2022, 204(11): 686.
tium infection and intestinal inflammation[J]. Gut Microbes, [26] Gaytán MO, Martínez-Santos VI, Soto E, et al. Type three se-
2021, 13(1): 1972757. cretion system in attaching and effacing pathogens[J]. Front
[11] Bilotta AJ, Ma CY, Yang WJ, et al. Propionate enhances cell Cell Infect Microbiol, 2016, 6: 129.
speed and persistence to promote intestinal epithelial turnover [27] Hemrajani C, Marches O, Wiles S, et al. Role of NleH, a type
and repair[J]. Cell Mol Gastroenterol Hepatol, 2021, 11(4): III secreted effector from attaching and effacing pathogens, in
1023-1044. colonization of the bovine, ovine, and murine gut[J]. Infect Im-
[12] Hou YF, Shan C, Zhuang SY, et al. Gut microbiota-derived pro- mun, 2008, 76(11): 4804-4813.
pionate mediates the neuroprotective effect of osteocalcin in a [28] Ruano-Gallego D, Sanchez-Garrido J, Kozik Z, et al. Type III
mouse model of Parkinson’s disease[J]. Microbiome, 2021, secretion system effectors form robust and flexible intracellular
9(1): 34. virulence networks[J]. Science, 2021, 371(6534): eabc9531.
[13] Killingsworth J, Sawmiller D, Douglas Shytle R. Propionate [29] Xiao Y, Huang XS, Zhao Y, et al. Interleukin-33 promotes
and Alzheimer’s disease[J]. Front Aging Neurosci, 2021, 12: REG3γ expression in intestinal epithelial cells and regulates gut
580001. microbiota[J]. Cell Mol Gastroenterol Hepatol, 2019, 8(1): 21-
[14] Ji QR, Zhang Y, Zhou YL, et al. Effects of hypoxic exposure on 36.
immune responses of intestinal mucosa to Citrobacter colitis in [30] Sonnenberg GF, Fouser LA, Artis D. Border patrol: regulation
mice[J]. Biomed Pharmacother, 2020, 129: 110477. of immunity, inflammation and tissue homeostasis at barrier
[15] Parada VD, De la Fuente MK, Landskron G, et al. Short chain surfaces by IL-22[J]. Nat Immunol, 2011, 12(5): 383-390.
fatty acids (SCFAs)-mediated gut epithelial and immune regula- [31] Backert I, Koralov SB, Wirtz S, et al. STAT3 activation in Th17
tion and its relevance for inflammatory bowel diseases[J]. Front and Th22 cells controls IL-22-mediated epithelial host defense
Immunol, 2019, 10: 277. during infectious colitis[J]. J Immunol, 2014, 193(7): 3779-
[16] Tong LC, Wang Y, Wang ZB, et al. Propionate ameliorates 3791.
dextran sodium sulfate-induced colitis by improving intestinal [32] Rubino SJ, Geddes K, Girardin SE. Innate IL-17 and IL-22 re-
barrier function and reducing inflammation and oxidative sponses to enteric bacterial pathogens[J]. Trends Immunol,
stress[J]. Front Pharmacol, 2016, 7: 253. 2012, 33(3): 112-118.
[17] Vinolo MAR, Rodrigues HG, Hatanaka E, et al. Suppressive ef- [33] Sha SS, Dong SR, Yang YJ. Research progress in gut microbio-
fect of short-chain fatty acids on production of proinflammato- ta and metabolites regulating host intestinal immunity[J].
ry mediators by neutrophils[J]. J Nutr Biochem, 2011, 22(9): Biotechnol Bull (生物技术通报), 2023, 39(8): 126-136.
849-855. [34] Li YJ, Xu KL, Pan XY. Research progress of CD4+T cells[J].
[18] Gao WW, Fang ZY, Lei L, et al. Propionate alleviates palmitic Int J Blood Transf Hematol, 2010, 33(1): 80-83.
acid-induced endoplasmic reticulum stress by enhancing au- [35] Stockinger B. T cell subsets and environmental factors in Cit-
tophagy in calf hepatic cells[J]. J Dairy Sci, 2021, 104(8): 9316- robacter rodentium infection[J]. Curr Opin Microbiol, 2021,
9326. 63: 92-97.
[19] Aschenbach JR, Kristensen NB, Donkin SS, et al. Gluconeoge- [36] Wang Z, Friedrich C, Hagemann SC, et al. Regulatory T cells
nesis in dairy cows: the secret of making sweet milk from sour promote a protective Th17-associated immune response to in-
dough[J]. IUBMB Life, 2010, 62(12): 869-877. testinal bacterial infection with C. rodentium[J]. Mucosal Im-
[20] Zhang F, Nan XM, Wang H, et al. Research on the applications munol, 2014, 7(6): 1290-1301.
of calcium propionate in dairy cows: a review[J]. Animals [37] Ding J, Bai X, Wang XL, et al. Immune cell responses and cy-
(Basel), 2020, 10(8): 1336. tokine profile in intestines of mice infected with Trichinella spi-
[21] Filippone A, Lanza M, Campolo M, et al. The anti-inflammato- ralis[J]. Front Microbiol, 2017, 8: 2069.