Page 208 - 《水产学报》2026年第3期

3 期 聂 蒙，等：罗非鱼源无乳链球菌缺失株 ΔcrRNA 与 ΔcpsE 的毒力与免疫效力 50 卷

coccus agalactiae[J]. Emerging Microbes & Infections, 2021, 2023, 51(W1): W587-W592.
10(1): 2113-2124. [21] Thakur A K, Fezio W L. A computer program for estimating
[11] Nie M, Dong Y H, Cao Q, et al. CRISPR contributes to adhe- LD 50 and its confidence limits using modified Behrens-Reed-
sion, invasion, and biofilm formation in Streptococcus agalac- Muench cumulant method[J]. Drug and Chemical Toxicology,
tiae by repressing capsular polysaccharide production[J]. 1981, 4(3): 297-305.
Microbiology Spectrum, 2022, 10(4): e02113-21. [22] Gao Y L, Tang X Q, Sheng X Z, et al. Antigen uptake and
[12] Zhang D F, Ke X L, Liu Z G, et al. Capsular polysaccharide of expression of antigen presentation-related immune genes in
Streptococcus agalactiae is an essential virulence factor for flounder (Paralichthys olivaceus) after vaccination with an
infection in Nile tilapia (Oreochromis niloticus Linn. )[J]. inactivated Edwardsiella tarda immersion vaccine, following
Journal of Fish Diseases, 2019, 42(2): 293-302. hyperosmotic treatment[J]. Fish & Shellfish Immunology, 2016,
[13] Chang Y C, Olson J, Beasley F C, et al. Group B Streptococcus 55: 274-280.
engages an inhibitory Siglec through sialic acid mimicry to [23] Xiong W, Guo C B, Gozlan R E, et al. Tilapia introduction in
blunt innate immune and inflammatory responses in vivo[J]. China: economic boom in aquaculture versus ecological threats
PLoS Pathogens, 2014, 10(1): e1003846. to ecosystems[J]. Reviews in Aquaculture, 2023, 15(1): 179-
[14] Pena J M S, Lannes-Costa P S, Nagao P E. Vaccines for Strep- 197.
tococcus agalactiae: current status and future perspectives[J]. [24] Liu G J, Zhu J L, Chen K M, et al. Development of Streptococ-
Frontiers in Immunology, 2024, 15: 1430901. cus agalactiae vaccines for tilapia[J]. Diseases of Aquatic
[15] Zhang D F, Gao Y X, Li Q Y, et al. An effective live attenu- Organisms, 2016, 122(2): 163-170.
ated vaccine against Streptococcus agalactiae infection in [25] 袁伟, 张德锋, 可小丽, 等. 中国罗非鱼主养区无乳链球菌流
farmed Nile tilapia (Oreochromis niloticus)[J]. Fish & Shell- 行菌株的菌毛岛屿及其血清型分型 [J]. 中国预防兽医学报,
fish Immunology, 2020, 98: 853-859. 2018, 40(6): 490-494.
[16] 聂蒙, 马可, 曹青, 等. 无乳链球菌 GD201008-001 二元调控 Yuan W, Zhang D F, Ke X L, et al. The pilus islands and
系统 RscSR 的鉴定及其对细菌应激适应性和毒力特性的影 molecular serotype of Streptococcus agalactiae isolated from
响 [J]. 水产学报, 2021, 45(9): 1545-1554. tilapia in the major tilapia-culturing areas in China[J]. Chinese
Nie M, Ma K, Cao Q, et al. Identification of two-component Journal of Preventive Veterinary Medicine, 2018, 40(6): 490-
system RscSR in Streptococcus agalactiae GD201008-001 and 494 (in Chinese).
its influence on the bacterial stress response and virulence[J]. [26] Zhang D F, Liu Z G, Ren Y, et al. Epidemiological characterist-
Journal of Fisheries of China, 2021, 45(9): 1545-1554 (in ics of Streptococcus agalactiae in tilapia in China from 2006 to
Chinese). 2020[J]. Aquaculture, 2022, 549: 737724.
[17] Hao J W, Wang S Y, Wei Z H, et al. Construction of Strepto- [27] 赵博, 张娜. 无乳链球菌血清型及其荚膜多糖疫苗的研究进
coccus agalactiae sialic acid mutant and evaluation of its poten- 展 [J]. 国外医药 (抗生素分册), 2025, 46(1): 45-51.
tial as a live attenuated vaccine in Nile tilapia (Oreochromis Zhao B, Zhang N. Development on serotypes and vaccines of
niloticus)[J]. Journal of Applied Microbiology, 2022, 133(4): Streptococcus agalactiae[J]. World Notes on Antibiotics, 2025,
2403-2416. 46(1): 45-51 (in Chinese).
[18] Ai K T, Li K, Jiao X Y, et al. IL-2-mTORC1 signaling coordin- [28] Minor P D. Live attenuated vaccines: historical successes and
ates the STAT1/T-bet axis to ensure Th1 cell differentiation and current challenges[J]. Virology, 2015, 479-480: 379-392.
anti-bacterial immune response in fish[J]. PLoS Pathogens, [29] Hao J W, Wang S Y, Yang J C, et al. Attenuated Streptococcus
2022, 18(10): e1010913. agalactiae WC1535 ∆Sia perturbs the gut microbiota of Oreo-
[19] Minh B Q, Schmidt H A, Chernomor O, et al. IQ-TREE 2: new chromis niloticus, massively colonizes the intestine, and
models and efficient methods for phylogenetic inference in the induces intestinal mucosal immunity after intraperitoneal inocu-
genomic era[J]. Molecular Biology and Evolution, 2020, 37(5): lation[J]. Frontiers in Microbiology, 2022, 13: 1036432.
1530-1534. [30] Xu C, Li E C, Suo Y T, et al. Histological and transcriptomic
[20] Xie J M, Chen Y R, Cai G J, et al. Tree Visualization By One responses of two immune organs, the spleen and head kidney,
Table (tvBOT): a web application for visualizing, modifying in Nile tilapia (Oreochromis niloticus) to long-term hypersaline
and annotating phylogenetic trees[J]. Nucleic Acids Research, stress[J]. Fish & Shellfish Immunology, 2018, 76: 48-57.

中国水产学会主办 sponsored by China Society of Fisheries https://www.china-fishery.cn
9