Page 71 - 《水产学报》2025年第11期

苏金枝，等 水产学报, 2025, 49(11): 119606

通，从而改善整体肠道通透性 。研究表明自 (in Chinese).
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噬及其调节机制参与了肠道的稳态和修复，通 [ 6 ] 陈秀梅, 高东旭, 李祖洋, 等. 虾青素对黄颡鱼生长、体色及
过紧密连接调节和保护细胞死亡来支持肠道屏 抗氧化的影响 [J]. 饲料工业, 2022, 43(4): 21-24.
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障功能 。由此证明自噬在虾青素调节肠道屏 Chen X M, Gao D X, Li Z Y, et al. Effects of astaxanthin on
障功能中发挥重要作用。 growth, body color and antioxidation of Pelteobagrus
fulvidraco[J]. Feed Industry, 2022, 43(4): 21-24 (in Chinese).
4 结论 [ 7 ] Zhu X W, Hao R J, Zhang J P, et al. Dietary astaxanthin

improves the antioxidant capacity, immunity and disease resist-
本研究揭示了饲喂虾青素的赤点石斑鱼
ance of coral trout (Plectropomus leopardus)[J]. Fish & Shell-
HSI 变化与肝脏脂质积累及代谢的关系，观察
fish Immunology, 2022, 122: 38-47.
了虾青素诱导自噬清除细胞中多余脂滴和受损
[ 8 ] 孙琳琳. 垂盆草苷对罗非鱼脂肪肝疗效的差异蛋白质组学研
线粒体、影响肠上皮细胞微绒毛和紧密连接结
究 [D]. 南宁: 广西大学, 2019.
构的现象，探讨了自噬在虾青素调节肝脏脂质
Sun L L. Differential proteomics study on the effect of sar-
代谢、减轻氧化应激和促进肠道屏障功能中的
mentosin on fatty liver in tilapia[D]. Nanning: Guangxi Uni-
作用，为虾青素在鱼类饲料中进一步开发利用
versity, 2019 (in Chinese).
提供实验依据。前期实验验证虾青素对赤点石
[ 9 ] 周文豪. 蛋白激酶 AMPK 在团头鲂脂肪肝发生中的作用及
斑鱼的生长没有显著影响，但在体色方面，虾 羟基酪醇对脂肪代谢的调控 [D]. 厦门: 集美大学, 2019.
青素增强了赤点石斑鱼的红度 a 和黄度 b 值， Zhou W H. Effects of AMPK on fatty liver of blunt snout
*
*
电子显微镜观察到背鳍、腹鳍、胸鳍、臀鳍和 bream (Megalorama amblycephala) and the regulation of
尾鳍中的黄色素细胞也明显增多，同时虾青素 hydroxytyrosol on lipid metabolism[D]. Xiamen: Jimei Uni-
显著提高了赤点石斑鱼的抗氧化能力，因此本 versity, 2019 (in Chinese).
研究认为虾青素诱导的自噬对赤点石斑鱼的生 [10] Yang J P, Shin J H, Seo S H, et al. Effects of antioxidants in
理代谢是有益的。 reducing accumulation of fat in hepatocyte[J]. International
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