Page 60 - 《中国药科大学学报》2025年第4期

456 学报 Journal of China Pharmaceutical University 2025, 56(4): 453 − 459 第 56 卷

(Continued)
Compd. 1 H NMR (400 MHz) 13 C NMR (100 MHz)
(Chloroform-d) δ 8.14 (t, J = 5.3 Hz, 1 H), 7.41 – 7.35 (m, 1 H), 7.30 (Chloroform-d) δ 179.75, 174.04, 173.97, 173.66, 139.90,
I 5
(td, J 1 = 5.6, J 2 = 1.1 Hz, 1 H), 7.25 – 7.16 (m, 2 H), 6.49 – 6.43 (t, 137.86, 133.11, 132.78, 130.46, 127.65, 125.63, 120.64
J = 6.5 Hz, 1 H), 5.43 – 5.37 (m, 1 H), 5.16 (td, J 1 = 8.1, J 2 = 3.4 74.37, 69.69, 64.91, 53.76, 48.01, 47.62, 47.44, 43.85,
Hz, 1 H), 5.08 (d, J = 7.7 Hz, 1 H), 3.85 (d, J = 8.9 Hz, 1 H), 3.59 42.54, 42.08, 39.80, 39.59, 39.02, 37.76, 37.55, 36.14,
(dd, J 1 = 9.4, J 2 = 4.6 Hz, 2 H), 3.53 – 3.44 (m, 1 H), 3.32 – 3.22 35.89, 32.18, 30.81, 29.78, 27.82, 27.70, 24.80, 23.48,
(m, 1 H), 3.15 – 3.07 (m, 1 H), 2.46(s,3 H), 2.08(s, 3 H), 2.02(s,3 23.09, 21.20, 20.18, 17.83, 17.21, 17.00, 16.87, 13.94,
H), 1.98(s, 3 H), 1.73 (d, J = 10.3 Hz, 2 H), 1.09 (d, J = 1.4 Hz, 6 9.32, 9.25, 9.11.
H), 0.95 (t, J = 1.6 Hz, 3 H), 0.88 (d, J = 3.2 Hz, 6 H), 0.78(s, 3 H).

I 6 (Chloroform-d) δ 8.07 (dd, J 1 = 8.6, J 2 = 5.5 Hz, 2 H), 7.49 (t, J = (Chloroform-d) δ 178.18, 170.82, 170.42, 167.96, 164.82,
5.6 Hz, 1 H), 7.37 (t, J = 8.7 Hz, 2 H), 5.15 (d, J = 3.7 Hz, 1 H), 5.00 139.63, 138.80, 134.76, 132.74, 131.14, 127.27, 125.19,
(td, J 1 = 10.9, J 2 = 4.5 Hz, 1 H), 4.90 (d, J = 10.3 Hz, 1 H), 4.19 (t, 74.77, 69.79, 65.24, 64.63, 53.61, 47.82, 47.51, 47.41,
J = 5.4 Hz, 2 H), 3.63 (dd, J 1 = 120.2, J 2 = 11.8 Hz, 2 H), 3.38 (d, 43.73, 42.40, 41.89, 39.67, 39.52, 39.00, 38.61, 37.67,
J = 5.6 Hz, 2 H), 1.99 (s, 3 H), 1.97 (s, 3 H), 1.91 (s, 3 H), 1.02 (s, 3 H), 37.22, 32.18, 30.80, 27.71, 26.91, 24.74, 23.29, 23.17,
0.91 (s, 3 H), 0.84 (s, 3 H), 0.81 (s, 3 H), 0.79 (s, 3 H), 0.59 (s, 3 H). 21.20, 21.06, 20.86, 20.77, 17.83, 17.18, 16.94, 16.79,
13.88.
(Chloroform-d) δ 7.83 (d, J = 8.4 Hz, 1 H), 7.52 (d, J = 2.0 Hz, 1 H), (Chloroform-d) δ 178.21, 170.92, 170.51, 170.48, 164.91,
I 7
7.35 (dd, J 1 = 8.4, J 2 = 2.0 Hz, 1 H), 6.27 – 6.13 (m, 1 H), 5.25 (t, 139.72, 138.90, 134.85, 132.82, 131.21, 127.35, 125.27,
J = 3.5 Hz, 1 H), 5.15 (td, J = 11.1, J 2 = 10.7, J 3 = 4.6 Hz, 1 H), 5.07 74.79, 69.81, 65.25, 64.64, 53.63, 47.83, 47.53, 47.42,
(d, J = 10.3 Hz, 1 H), 4.41 (dd, J 1 = 15.3, J 2 = 2.9 Hz, 2 H), 3.84 (d, 43.75, 42.41, 41.85, 39.65, 39.51, 39.01, 38.60, 37.65,
J = 11.8 Hz, 1 H), 3.76 (d, J = 3.8 Hz, 1 H), 3.58 (d, J = 11.8 Hz, 1 37.21, 32.15, 30.81, 27.70, 26.92, 24.73, 23.25, 23.17,
H), 3.43 (d, J = 7.1 Hz, 1 H), 2.08 (s, 3 H), 2.02 (s, 3 H), 1.98 (s, 3 21.21, 21.06, 20.87, 20.79, 17.84, 17.19, 16.93, 16.81,
H), 1.08 (s, 3 H), 1.01 (s, 3 H), 0.95 (s, 3 H), 0.88 (s, 3 H), 0.87 – 13.89.
0.85 (m, 3 H), 0.74 (s, 3 H).
(Chloroform-d) δ 7.05 (t, J = 5.5 Hz, 1 H), 5.20 (d, J = 3.7 Hz, 1 H), (Chloroform-d) δ 178.75, 174.14, 174.05, 173.74, 158.97,
I 8
5.05 (dt, J 1 = 11.1, J 2 = 5.5 Hz, 1 H), 4.93 (d, J = 10.3 Hz, 1 H), 139.72, 125.30, 77.48, 76.84, 69.81, 65.02, 53.63, 47.89,
4.59 (t, J = 5.4 Hz, 1 H), 3.81 (d, J = 11.0 Hz, 1 H), 3.50 (d, J = 11.7 47.56, 43.96, 42.54, 39.85, 39.69, 39.09, 37.87, 37.58,
Hz, 1 H), 3.31 (s, 6 H), 3.13 (m, 1 H), 3.03 – 2.96 (m, 1 H), 2.00 (s, 37.13, 36.31(2C), 35.70, 32.37, 30.99, 30.49, 27.91, 27.80,
3 H), 1.98 (s, 3 H), 1.92 (s, 3 H), 1.04 (d, J = 8.7 Hz, 6 H), 0.92 (s, 3 23.23, 21.32, 17.95, 17.27, 17.09, 16.99, 14.04, 9.40, 9.33,
H), 0.83 (s, 6 H), 0.71 (s, 3 H). 9.19.
(Chloroform-d) δ 7.94 (d, J = 8.5 Hz, 2 H), 6.88 (d, J = 8.5 Hz, 2 H), (Chloroform-d) δ 178.18, 170.82, 170.42, 170.38, 164.82,
I 9
6.17 (t, J = 5.4 Hz, 1 H), 5.15 (t, J = 3.5 Hz, 1 H), 5.05 (td, J 1 = 139.63, 138.80, 134.76, 132.74, 131.14, 128.05, 127.27,
10.7, J 2 = 4.4 Hz, 1 H), 4.98 (d, J = 10.3 Hz, 1 H), 4.36 – 4.25 (m, 2 125.19, 74.77, 69.79, 65.24, 64.63, 58.68, 53.61, 47.82,
H), 3.82 (s, 3 H), 3.75 (d, J = 11.8 Hz, 1 H), 3.63 (d, J = 5.4 Hz, 1 47.51, 47.41, 43.73, 42.40, 39.67, 39.52, 39.00, 38.61,
H), 3.50 (d, J = 11.8 Hz, 1 H), 3.43 – 3.34 (m, 1 H), 2.00 (s, 3 H), 37.67, 37.22, 32.18, 30.80, 27.71, 26.91, 24.74, 23.29,
1.95 (s, 3 H), 1.91 (s, 3 H), 0.99 (s, 3 H), 0.87 (d, J = 3.6 Hz, 6 H), 23.17, 21.20, 21.06, 20.86, 20.77, 17.83, 17.18, 16.94,
0.79 (s, 3 H), 0.77 (d, J = 6.4 Hz, 3 H), 0.64 (s, 3H). 16.79, 13.88.
II 1 (Chloroform-d) δ 7.90 (dd, J 1 = 6.4, J 2 = 4.2 Hz, 2 H), 7.55 (t, J = (Chloroform-d) δ 177.98, 168.15, 135.58, 134.79, 131.06,
4.8 Hz, 1 H), 7.10 (t, J = 6.4 Hz, 2 H), 6.29 (t, J = 4.5 Hz, 1 H), 5.41 129.69 (2C), 128.54, 127.78 (2C), 78.45, 78.14, 76.88,
(t, J = 2.7 Hz, 1 H), 4.61 (q, J = 4.8 Hz, 1 H), 4.54 (d, J = 7.7 Hz, 1 59.26, 56.69, 53.27, 48.64, 47.94, 47.63, 47.40, 43.95,
H), 4.22 (d, J = 8.8 Hz, 1 H), 4.07 (dd, J 1 = 10.2, J 2 = 5.1 Hz, 1 H), 42.40, 42.38, 42.11, 39.66, 38.93, 37.81, 37.60, 37.35,
3.87 (d, J = 8.8 Hz, 2 H), 3.53(s, 1 H), 3.42(s, 1 H), 3.36 (dd, J 1 = 35.81, 35.27, 32.47, 30.98, 27.87, 26.35, 24.67, 23.47,
8.2, J 2 = 3.0 Hz, 2 H), 3.31(s, 1 H), 1.61 (dd, J 1 = 7.7, J 2 = 5.3 Hz,2 21.24, 21.19, 18.11, 17.14, 16.92, 13.64.
H), 1.09(s, 3 H), 0.94 (d, J = 2.6 Hz, 6 H), 0.88 – 0.84 (m, 6 H), 0.65
(d, J = 2.0 Hz, 3 H).
(Chloroform-d) δ 8.02 (d, J = 6.0 Hz,2 H), 7.85 (t, J = 4.7 Hz,1 H), (Chloroform-d) δ 178.07, 168.26, 135.69, 134.91, 131.12,
II 2
7.71 (d, J = 6.0 Hz,2 H), 6.29 (t, J = 4.8 Hz), 5.41 (t, J = 2.7 Hz), 129.71(2C), 128.65, 127.78(2C), 125.35, 78.46, 77.23,
3.53(s, 1 H), 3.42(s, 1 H), 3.39 – 3.33 (m,2 H), 3.31(s,1 H), 3.11 (td, 76.87, 59.28, 56.71, 53.29, 48.65, 47.96, 47.61, 47.38,
J 1 = 7.2, J 2 = 1.7 Hz, 4 H), 3.05 (d, J = 7.0 Hz, 2 H), 1.61 (dd, J 1 = 43.95, 42.65, 42.29, 42.11, 39.67, 38.93, 37.82, 37.61,
7.7, J 2 = 5.3 Hz, 2 H), 1.09 (s, 3 H), 0.94 (d, J = 2.6 Hz, 6 H), 0.88 – 37.36, 35.82, 35.28, 32.47, 30.98, 27.88, 26.36, 24.68,
0.83 (m, 6 H), 0.65 (d, J = 2.0 Hz, 3 H). 23.43, 23.36, 21.21, 18.12, 17.13, 13.65.
(Chloroform-d) δ 8.16 (t, J = 4.6 Hz,1 H), 7.45 (d, J = 1.9 Hz, 1 H), (Chloroform-d) δ 177.99, 168.16, 135.59, 134.80, 131.09,
7.33 (dd, J 1 = 8.2, J 2 = 2.0 Hz, 1 H), 7.23 (d, J = 8.1 Hz, 1 H), 6.71 129.70 (2C), 128.55, 127.79 (2C), 78.47, 78.15, 76.89,
(t, J = 6.1 Hz, 1 H), 5.41 (t, J = 3.6 Hz, 1 H), 3.48 (d, J = 9.5 Hz, 2 59.27, 56.70, 53.28, 48.64, 47.95, 47.64, 47.40, 43.96,
II 3 H), 3.40 (d, J = 4.8 Hz, 5 H), 3.33 (s, 3 H), 3.31 – 3.25 (m, 2 H), 42.41, 42.38, 42.11, 39.66, 38.93, 37.81, 37.60, 37.35,
3.14 – 3.09 (m, 2 H), 2.82 (s, 3 H), 1.62 (t, J = 8.5 Hz, 2 H), 0.99 (s, 35.81, 35.27, 32.47, 30.98, 27.87, 26.35, 24.67, 23.47,
3 H), 0.94 (s, 3 H), 0.87 (dd, J 1 = 6.3, J 2 = 1.7 Hz, 6 H), 0.79 (d, J = 23.37, 21.24, 18.11, 17.14, 16.92, 13.64.
7.4 Hz, 6 H).