Page 10 - 《渔业研究》2026年第3期

金笑延等： 基于转录组学和代谢组学分析选育系 F 5 代与非选育系马苏大麻哈鱼卵基因表达及
第 3 期
LLMS2 LLMS3 LLMS1 LLMS4 LLMS5 LBSMS1 LBSMS3 LBSMS4 LBSMS2 LBSMS5 Tolmetin glucuronide
图 6
Fig. 6 Heatmap of the hierarchical clustering of DEMs
注：图中相对含量的大小通过颜色的不同来显示，颜色越红，表达量越高；颜色越蓝，表达量越低。其中，列代表样
本，行代表差异表达代谢物，左侧的聚类树为差异表达代谢物聚类树。
Notes: The size of the relative content in the figure is shown by the different colors. The red the color, the higher the expression,
while the bluer the lower the expression. Where columns represent samples, rows represent DEMs, and the cluster tree on the left of the
figure is DEMs cluster tree.
3 讨论
鱼卵中富含蛋白质、脂肪、氨基酸等营养物质，
具有极大的开发利用空间 [18] 。在鱼类卵子发育过
程中，母体将营养物质转移至卵母细胞中，进一步
发育成熟后便排至卵巢中，此时即形成了完整的卵
子 [19] 。有研究指出，暗纹东方鲀（Takifugu obscurus）
不同质量卵内部生理生化成分存在差异，卵内生理
代谢物水平的差异 303
组别 Groups 组别 Groups
Cyanidin 3−O−(2\
86_3,6−Epoxy−5,5',6,6'−tetrahydro−b,b−carotene−3',5,5.... 2 1 0 −1 LBSMS
Gymnodimine
170_PE−NMe(18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z)....
PE(15:0/18:3(6Z,9Z,12Z))
PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)−OH(20))
28−Glucopyranosyl−3−methyloleanolic acid
PC(22:1(13Z)/LTE4)
LysoPE(0:0/24:6(6Z,9Z,12Z,15Z,18Z,21Z))
Elarofiban
505_5−(2−Furanyl)−1,2,3,4,5,6−hexahydro−7H−cyclopenta[....
LLMS
SM(d18:1/PGE2)
155_PE−NMe(20:5(5Z,8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,....
PC(14:1(9Z)/18:4(6Z,9Z,12Z,15Z))
LysoPC(20:2(11Z,14Z)/0:0)
95_PE−NMe(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)....
PE(18:2(9Z,12Z)/PGE1)
PE(20:4(5Z,8Z,11Z,14Z)/PGE1)
PC(18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z))
LysoPE(20:1(11Z)/0:0)
388_2,4,5,7alpha−Tetrahydro−1,4,4,7a−tetramethyl−1H−in....
PG(i−22:0/20:4(5Z,8Z,11Z,14Z)−OH(20))
PG(i−22:0/20:5(5Z,8Z,11Z,14Z,16E)−OH(18))
PE(DiMe(11,5)/MonoMe(13,5))
Hexyl 2−furoate
Quercetin 3−arabinoside 7−glucoside
LysoPC(22:4(7Z,10Z,13Z,16Z)/0:0)
Anhydroamarouciaxanthin B
160_PE−NMe(18:4(6Z,9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,....
PE(16:0/PGE2)
76_4−Tert−butyl−N−[6−(2−hydroxyethoxy)−5−(3−methoxyph....
LysoPE(14:0/0:0)
Gluten exorphin C
PI(18:2(9Z,12Z)/6 keto−PGF1alpha)
PI(16:0/6 keto−PGF1alpha)
PC(P−16:0/PGF1alpha)
PC(16:0/18:1(12Z)−O(9S,10R))
PC(2:0/20:5(5Z,8Z,11Z,14Z,16E)−OH(18R))
Elatoside G
PE−NMe(14:0/18:4(6Z,9Z,12Z,15Z))
SM(d18:1/14:1(9Z))
Triphasiaxanthin
Azadirachtin
Sirolimus
1−[(5−Amino−5−carboxypentyl)amino]−1−deoxyfructose
(2S,2'S)−Pyrosaccharopine
LysoPC(20:1(11Z)/0:0)
4−Hydroxybenzoyl glucose
6−methylthiohexyldesulfoglucosinolate
CDP−DG(18:3(6Z,9Z,12Z)/PGE2)
PE(14:0/PGF1alpha)
LysoPE(20:2(11Z,14Z)/0:0)
Gravacridonetriol glucoside
395_Kaempferol 3−O−feruloyl−caffeoyl−sophoroside 7−O−g....
PE(DiMe(13,5)/20:4(5Z,8Z,11Z,14Z)−OH(20))
PC(20:0/20:5(5Z,8Z,11Z,14Z,16E)−OH(18R))
Daumone
11beta−Hydroxy−3,20−dioxopregn−4−en−21−oic acid
1−Nonadecanoyl−glycero−3−phosphoethanolamine
Pulchinenoside A
PA(24:0/PGF1alpha)
516_(2S)−2−Amino−6−[(3−formylpiperidin−1−yl)amino]hexa....
10,11−Dihydro−12R−hydroxy−leukotriene E4
Epothilone B
Tetrahydrogestrinone
Lactose−lysine
Pimecrolimus
11−Oxo−androsterone glucuronide
239_b−D−Glucuronopyranosyl−(1−>3)−a−D−galacturonopyran....
456_PG(i−22:0/22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S, 17S)....
L−Agaritine
Taurodeoxycholic acid 3−glucuronide
N'−Formylkynurenine
Gentianine
6−Hydroxy−3,4−dihydro−2(1H)−quinolinone
alpha−Cephalin
552_3'−Azido−3'−deoxy−5'− O−beta−D−glucopyranuronosylt....
gamma−Glutamylisoleucine
CDP−DG(6 keto−PGF1alpha/i−19:0)
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:3(6,8,11)−OH(5))
TG(16:0/16:0/18:2(9Z,12Z))
TG(16:1(9Z)/18:1(9Z)/18:1(9Z))
Crocin 3
Obacunone 17−O−beta−D−glucoside
Terazosin
PI(18:1(11Z)/6 keto−PGF1alpha)
O−(17−Carboxyheptadecanoyl)carnitine
Neomycin
Peanut oil, hydrogenated
N−(1−Deoxy−1−fructosyl)isoleucine
Cysteineglutathione disulfide
Pelargonidin 3−sophoroside
2−hydroxy−3−methylbutanedioylcarnitine
N−(1−Deoxy−1−fructosyl)phenylalanine
Mimosine
N−Acetyl−9−O−acetylneuraminic acid
Artemin
6−Methoxyluteolin 7−glucuronide
2−Fluoroadenosine
47_(2S)−3−[3−[(4−Carbamimidoylbenzoyl)amino]propanoyl....
Valylglutamic acid
N−Arachidonoyl Aspartic acid
PS(24:0/20:3(5Z,8Z,11Z)−O(14R,15S))
Riesling acetal
1−(3−Methyl−2−butenoyl)−6−apiosylglucose
512_(1R,2R,3S,5S)−3−Hydroxy−4−(4−hydroxybenzoyl)−8−met....
Thymidine glycol
N−(1−Deoxy−1−fructosyl)threonine
2−O−Methylascorbic acid
Pgg−glucan
N,N'−diacetylchitobiose
521_(2R)−2−[[(2S,3R)−3−Amino−2−hydroxy−4−phenyl−butano....
MG(20:4(5Z,8Z,11Z,14Z)−OH(20)/0:0/0:0)
Curdione
O−[(9Z)−17−Carboxyheptadec−9−enoyl]carnitine
374_(10E,12E,14E)−16−Hydroxy−9−oxooctadeca−10,12,14−tr....
4−Androstenediol
Aplotaxene
7−Hydroxycostol
Aspergillomarasmine A
PI(16:2(9Z,12Z)/PGD1)
3−Hydroxydodeca−7,10−dienoylcarnitine
(10E)−8−Hydroxydodec−10−enoylcarnitine
MG(18:3(9,11,15)−OH(13)/0:0/0:0)
8−Hydroxyhexadecanedioylcarnitine
O−(13−Carboxytridecanoyl)carnitine
(8Z)−3−Hydroxydodec−8−enoylcarnitine
Glutamylmethionine
Dopamine glucuronide
Radalbuvir
2−Hydroxyquinoline−3−carboxylic acid
Epothilone A
(2S)−2−Amino−3−(4−hydroxyphenyl)propane−1,1−diol
Gentamicin C2
1−Aminocyclohexanecarboxylic acid
(2S)−6−Amino−2−(hexanoylamino)hexanoic Acid
366_3−[4−Hydroxy−3−(3−methyl−2−butenyl)phenyl]−2−prope....
Butyl (S)−3−hydroxybutyrate glucoside
Imidazoleacetic acid ribotide
Sulfolithocholylglycine
Tuliposide A
6_1−[(2R,3R,4S,5R)−3,4−Dihydroxy−5−(hydroxymethyl)ox....
Glutamylproline
gamma−Glutamylserine
525_1−(2,3−Dihydro−6,7−dimethyl−1H−pyrrolizin−5−yl)−2−....
Nartograstim
Fumaryl diketopiperazine
Hept−4−enedioylcarnitine
PS(DiMe(11,3)/DiMe(13,5))
73_L−Asparagine, L−alanyl−L−tyrosyl−L−methionyl−L−thr....
Citrusin III
3,5−Dimethyl−3'−isopropyl−L−thyronine
gamma−Aminobutyric acid glutamate
9_Rubrofusarin 6−[glucosyl−(1−>3)−glucosyl−(1−>6)−gl....
cryptophycin
Succinyladenosine
Aspartyl−Leucine
(2E)−Hept−2−enedioylcarnitine
10−Hydroxydecanoic acid
5−(2−Aminopropyl)indole
Venlafaxine
Janthitrem B
Lysylhydroxyproline
Pyroglutamylglycine
Glutamyltyrosine
5−Phenyl−1,3−oxazinane−2,4−dione
Ile−Glu−Thr−Asp−fluoromethyl ketone
2−Hydroxy−4−carboxybutyrylhistidylprolinamide
7−Methylinosine
573_Methyl (3b,11x)−3−Hydroxy−8−oxo−6−eremophilen−12−o....
cis−4−Carboxymethylenebut−2−en−4−olide
Seryltyrosine
gamma−Glutamylvaline
Dibutyryl adenosine
Pyridinoline
S−(11−hydroxy−9−deoxy−delta12−PGD2)−glutathione
Valylproline
−2
(x)−2−Heptanol glucoside
PS(18:1(11Z)/20:4(6Z,8E,10E,14Z)−2OH(5S,12R))
433_DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,....
Glutamylisoleucine
Physalin A
Caffeoyl C1−glucuronide
L−Glutamine
3−hydroxy−docosapentaenoyl−CoA
Citrusin IV
Tsugaric acid A 21−glucosyl ester
1,6−anhydro−N−acetyl−beta−muramate
5,7−Megastigmadien−9−ol glucoside
Penitrem B
(4Z,6Z)−3−Hydroxyocta−4,6−dienoylcarnitine
Uridine
Formycin b
8−Oxo−2'−deoxyadenosine
CDP−DG(22:3(10Z,13Z,16Z)/LTE4)
Hydroxydestruxin B
5,6−Dihydro−5−azacytidine
Trypanothione disulfide
Metabolite M6
Agtad[cfwkyc]V
Disialyllacto−N−tetraose
Cyclo(glycylleucylvalylleucylprolylseryl)
Phosphoribosyl formamidocarboxamide
Lysylproline
5−Hydroxyindoleacetic acid
Seryllysine
2−amino−3,7−dideoxy−D−threo−hept−6−ulosonate
DG(2:0/PGE1/0:0)
Saquinavir−NO
L−quinate
2,3−Dinor−TXB2
APC
(6Z)−Oct−6−enedioylcarnitine
Glutamate nitrogen
Carboxyethyllysine
(R)−Pantothenic acid 4'−O−b−D−glucoside
Fasoracetam
Nicotinamide riboside
Dynorphin B (6−9)
(2E)−Tetradec−2−enedioylcarnitine
Dodecanedioylcarnitine
DG(2:0/5−iso PGF2VI/0:0)
Aspartyl−Tryptophan
Acetyl−Ser−Asp−Lys−Pro
Adrenochrome
Dictyoquinazol C
Dehydroepiandrosterone
3beta−Hydroxy−5,7−androstadien−17−one
6−Hydroxy−5−methoxyindole glucuronide
Mebendazole
Cichorioside N
CDP−DG(a−13:0/5−iso PGF2VI)
63_6−Oxo−1−phenyl−1,6−dihydropyridine−3−carboxylic ac....
Resolvin E1
PIP(PGJ2/22:4(10Z,13Z,16Z,19Z))
Phytosphingosine
Glycerophosphocholine
Proscillaridin
282_(1alpha,4beta,5beta)−4−Hydroxy−7(11),10(14)−guaiad....
2(1H)−Quinolinone, 3−methoxy−
Metabolite M
Tsangane L 3−glucoside
bicyclo−PGE2
148_(2R,3R)−3−[[(2S)−1−[4−(Diaminomethylideneamino)but....
20−Hydroxy−leukotriene B4
584_N−(3−Aminopropyl)−N−methylcarbamic acid tert−butyl....
Glutamylphenylalanine
Commodore
oxymetholone
Morroniside
(7b,10a)−3−Hydroxy−1,3,5−cadinatrien−9−one
3alpha−Hydroxytibolone
12−Hydroxydodecanoylcarnitine
PA(18:4(6Z,9Z,12Z,15Z)/PGJ2)
PC(20:2(11Z,14Z)/20:3(6,8,11)−OH(5))
64_(2S)−2−Amino−3−[(2S,3R)−2−amino−3−[(2S)−2−amino−3−....
6,8−Dihydroxypurine
3'−Deoxyinosine
12,20−Dioxo−leukotriene B4
Prednisolone
PC(16:0/16:1(9Z))
236_(8alpha,10alpha,13alpha,17beta)−17−[(4−Hydroxyphen....
1−Methylhistidine
CE(TXB2)
Farglitazar
483_(8Z,11Z,14Z,17Z)−Icosa−8,11,14,17−tetraenoylcarnit....
(11Z,14Z,17Z)−Icosa−11,14,17−trienoylcarnitine
Glycocholenate sulfate
(13Z)−Octadec−13−enoylcarnitine
9,10−DiHODE
LysoPG(18:1(9Z)/0:0)
Vitamin A2
17−Aminogeldanamycin
1−Oleoylglycerophosphoserine
Palmitoylcarnitine
196_15−deoxy−delta12,14−Prostaglandin J2−2−glycerol es....
PC(20:5(5Z,8Z,11Z,14Z,17Z)/PGF1alpha)
Pregnanetriol
Tetradecanoylcarnitine
20−HDoHE
8−Hydroxytrtradeca−10,12−dienoylcarnitine
(10Z,12E)−Tetradecadienoylcarnitine
1−Acetoxy−2−hydroxy−16−heptadecen−4−one
20−Hydroxyeicosatetraenoic acid
287_11−{3,4−Dimethyl−5−[(1E)−prop−1−en−1−yl]furan−2−yl....
3−Hydroxyheptadecanoylcarnitine
Cyanoginosin
Cilazapril
Dihydroneopine
PS(16:1(9Z)/24:1(15Z))
trans−zeatin riboside
Hovenidulcioside A2
Plumieride
252_1−[(2R,4R,5R)−5−(Aminomethyl)−4−hydroxyoxolan−2−yl....
Methionyl−Glutamate
Asparaginyl−Proline
Kahweol
347_2,5−diamino−6−(5−phospho−D−ribitylamino)pyrimidin−....
Glutathionate(1−)
Erythroskyrin
virginiamycin m1
5−HEPE
gamma−Glutamyltryptophan
PC(16:1(9Z)/18:1(9Z))
3−Hydroxycotinine glucuronide
Rosmaricine
20−Oxo−leukotriene E4
AB−Chminaca
5−Hydroxy−1−methylpyrrolidin−2−one
Stizolamine
Garcimangosone C
Isopropyl beta−D−glucoside
2−Methylbutyroylcarnitine
Isobutyryl−L−carnitine
3−Hydroxytetradecanoyl carnitine
Binfloxacin
Glucosamine
N2−(gamma−Glutamyl)−4−carboxyphenylhydrazine
Dehydroepiandrosterone acetate
364_6−(7−Hydroxy−6,7−dihydro−5H−pyrrolo[1,2−c]imidazol....
5−Benzylacyclouridine
Amoxicilloyl
Caryoptosidic acid
Minoxidil Glucuronide
MG(18:1(12Z)−2OH(9,10)/0:0/0:0)
Semilepidinoside A
PE(18:1(11Z)/20:4(7E,9E,11Z,13E)−3OH(5S,6R,15S))
PC(18:0/18:2(9Z,12Z))
Brincidofovir
PE(P−18:0/18:1(12Z)−2OH(9,10))
PS(24:0/PGF2alpha)
PC(18:1(11Z)/15:0)
PC(DiMe(11,3)/PGE2)
PE−NMe2(18:1(9Z)/18:1(9Z))
PC(22:0/20:5(7Z,9Z,11E,13E,17Z)−3OH(5,6,15))
59_Quillaic acid 3−[galactosyl−(1−>2)−[xylosyl−(1−>3)....
PZ−Peptide
Ponasterone A
Cyclic−(GVCRCICTRGFCRCLCRR)
Quil A
Hastatoside
442_PC(22:4(7Z,10Z,13Z,16Z)/20:5(5Z,8Z,11Z,14Z,16E)−OH....
PC(14:1(9Z)/5−iso PGF2VI)
PC(22:2(13Z,16Z)/PGJ2)
283_4−Amino−1−[(2R,3S,4S,5R)−3,4−dihydroxy−5−(hydroxym....
538_2,4(1H,3H)−Pyrimidinedione, 3−((2R)−2−amino−2−phen....
Prolyl−Gamma−glutamate
DG(18:1(11Z)/18:3(9Z,12Z,15Z)/0:0)
Triamcinolone acetonide 21−palmitate
11−beta−Hydroxyandrosterone−3−glucuronide
469_FAHFA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/14−O−22:6(4Z,7Z,....
Deoxypyridinoline
PC(15:0/P−18:1(11Z))
CL(18:0/18:0/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
CL(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0/18:0)
Haloperidol
Polymyxin M
PC(20:0/PGF2alpha)
PE(20:4(8Z,11Z,14Z,17Z)/22:0)
Arctiol
PC(14:1(9Z)/P−16:0)
PE−NMe2(14:1(9Z)/18:1(9Z))
Macrolactin−A
Testosterone isobutyrate
Estradiol 3−Valerate
Methyl (7Z,9Z,9'Z)−6'−apo−y−caroten−6'−oate
PE(O−16:0/18:1(9Z))
PS(20:3(8Z,11Z,14Z)/18:0)
1−(4−Methyl−5−thiazolyl)−1−phenylmethylamine
PE(P−16:0/18:1(12Z)−O(9S,10R))
PC(16:1(9Z)/5−iso PGF2VI)
PC(P−16:0/PGE2)
PC(PGF2alpha/16:1(9Z))
PC(PGE2/15:0)
PC(16:0/20:5(7Z,9Z,11E,13E,17Z)−3OH(5,6,15))
Tetrahydrocortisone
FAHFA(18:1(9Z)/12−O−18:0)
TG(15:0/18:2(9Z,12Z)/20:5(5Z,8Z,11Z,14Z,17Z))
TG(15:0/18:1(11Z)/20:3(5Z,8Z,11Z))
2−Hexadec−7−enylicosa−8,11−dienedioic acid
Muricatin C
DG(PGE2/16:0/0:0)
Cer(d18:1/24:1(15Z))
471_12,15−Epoxy−13,14−dimethyleicosa−12,14,16−trienoic....
Icosa−2,4,6−trienoic acid
SM(d18:1/26:1(17Z))
PE(18:1(11Z)/20:1(11Z))
PE(18:0/18:1(11Z))
LysoPI(0:0/18:0)
LysoPI(18:1(9Z)/0:0)
N(2)−phenylacetyl−L−glutaminate
LysoPI(16:0/0:0)
370_(E)−5−(3,4,5,6−Tetrahydro−3−pyridylidenemethyl)−2−....
PC(20:1(11Z)/PGE1)
DG(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)
PC(O−16:0/18:2(9Z,12Z))
PE(18:1(11Z)/24:1(15Z))
PC(22:3(10Z,13Z,16Z)/PGE2)
PE(22:0/PGD2)
9−O−Acetylneuraminic acid
PE(18:0/22:5(4Z,7Z,10Z,13Z,16Z))
PC(22:0/PGE2)
PE(18:1(11Z)/18:4(6Z,9Z,12Z,15Z))
PC(18:2(9Z,12Z)/24:1(15Z))
425_Isofucosterol 3−O−[6−O−(9,12−Octadecadienoyl)−b−D−....
DG(a−25:0/6 keto−PGF1alpha/0:0)
ubiquinone−8
Carene
PE(20:0/20:2(11Z,14Z))
PS(18:1(11Z)/24:1(15Z))
PE(20:2(11Z,14Z)/PGJ2)
PE(16:0/20:4(6E,8Z,11Z,13E)−2OH(5S,15S))
5−(1,2−Dihydroxyethyl)−4−hydroxyoxolane−2,3−dione
463_PC(22:3(10Z,13Z,16Z)/20:5(7Z,9Z,11E,13E,17Z)−3OH(5....
88_(R)−3,4−Dihydro−8−hydroxy−3−tridecyl−1H−2−benzopyr....
Neolicuroside
3−Amino−2−methoxynonadec−5−en−4−ol
LysoPG(16:0/0:0)
1−(11Z,14Z−eicosadienoyl)−glycero−3−phosphate
CPA(18:0/0:0)
Formylfusarochromanone
Corticosterone acetate
PE(18:0/18:2(9Z,12Z))
3−Indolehydracrylic acid
N−Acetylvanilalanine
Micronomicin
LysoPC(18:2(9Z,12Z)/0:0)
N−Linoleoyl GABA
PC(O−16:0/16:1(9Z))
PE(18:1(11Z)/18:2(9Z,12Z))
DG(20:0/20:5(7Z,9Z,11E,13E,17Z)−3OH(5,6,15)/0:0)
Polyporenic acid C
DL−Ethionine
DG(15:0/18:2(9Z,12Z)/0:0)
TG(15:0/16:1(9Z)/18:3(6Z,9Z,12Z))
DG(15:0/16:1(9Z)/0:0)
Rostafuroxin
(9S,10S)−9,10−dihydroxyoctadecanoate
PE(24:1(15Z)/6 keto−PGF1alpha)
SM(d17:1/24:1(15Z))
N−(Tricosanoyl)−4E,14Z−sphingadienine
SM(d18:0/23:0)
PC(18:0/P−16:0)
PC(20:5(5Z,8Z,11Z,14Z,17Z)/24:1(15Z))
PC(20:4(5Z,8Z,11Z,14Z)/24:1(15Z))
SM(d16:1/24:1(15Z))
PC(24:0/20:4(7E,9E,11Z,13E)−3OH(5S,6R,15S))
PC(DiMe(11,3)/DiMe(13,5))
Formyl−5−hydroxykynurenamine
3−(1,1−Dimethylallyl)scopoletin 7−glucoside
566_gamma−L−Glutamyl−S−(2−carboxy−1−propyl)cysteinylgl....
PA(16:0/24:1(15Z))
LysoPC(28:1(5Z)/0:0)
PC(O−14:0/16:1(9Z))
PE(15:0/24:1(15Z))
PS(18:1(9Z)/18:3(9Z,12Z,15Z))
PC(P−18:1(11Z)/18:0)
SM(d18:1/16:0)
PC(16:0/18:1(12Z)−2OH(9,10))
PS(18:2(9Z,12Z)/18:0)
DG(PGE2/18:0/0:0)
PC(O−16:1(9Z)/18:0)
PE−NMe2(15:0/20:1(11Z))
PC(O−18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
PE−NMe2(16:0/18:1(9Z))
PE−NMe2(16:0/20:1(11Z))
PE−NMe2(20:4(8Z,11Z,14Z,17Z)/24:0)
SM(d18:0/LTE4)
PC(24:1(15Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)−OH(4))
DG(18:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)
Morphine−6−glucuronide
PC(16:1(9Z)/PGJ2)
PE(18:0/PGF1alpha)
312_PC(18:2(9Z,12Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S....
PC(16:1(9Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)−OH(4))
PC(DiMe(13,5)/PGF1alpha)
PC(15:0/PGJ2)
PE(18:1(11Z)/PGJ2)
N−di−Demethyl roxithromycin
PE(18:3(9Z,12Z,15Z)/PGF2alpha)
SM(d18:0/24:1(15Z)(OH))
PE−NMe(16:0/18:1(9Z))
DG(21:0/0:0/LTE4)
LysoPC(24:0/0:0)
SM(d18:0/14:0)
PE−NMe(16:0/20:3(5Z,8Z,11Z))
LysoPC(26:1(5Z)/0:0)
PS(20:0/22:4(7Z,10Z,13Z,16Z))
PC(22:5(4Z,7Z,10Z,13Z,16Z)/24:1(15Z))
Cer(d18:0/16:0)
PC(20:5(5Z,8Z,11Z,14Z,17Z)/24:0)
3−Feruloylquinic acid
PS(20:1(11Z)/18:3(10,12,15)−OH(9))
4,8−Dimethylnonanoyl−CoA
TG(15:0/18:1(9Z)/18:3(9Z,12Z,15Z))
79_(8R,9S,10S,13S,14S,17R)−17−Ethyl−3,17−dihydroxy−10....
Carnosine
Acrimarine H
PE(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Enkephalinamide−Leu, Ala(2)−
PC(22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S, 17S)/18:0)
PS(16:0/22:1(13Z))
PC(18:2(9Z,12Z)/P−18:0)
DG(20:0/20:4(6Z,8E,10E,14Z)−2OH(5S,12R)/0:0)
Chembl4238926
Mytilin A
Tulathromycin A
Osmanthuside B
PC(6 keto−PGF1alpha/16:1(9Z))
PC(20:2(11Z,14Z)/PGF2alpha)
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/TXB2)
2−[(2S)−2,6−Diaminohexanoyl]oxyacetic acid
Pro−Pro−Pro
PC(2:0/18:3(10,12,15)−OH(9))
Pelargonidin 3−galactoside
115_CL(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z....
116_CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,....
3,11,12−Trihydroxy−1(10)−spirovetiven−2−one
25_PC(DiMe(13,5)/22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S, ....
PC(18:2(9Z,12Z)/PGJ2)
Threonylhydroxyproline
Demethoxyrapamycin
PE(22:2(13Z,16Z)/PGJ2)
PC(PGJ2/16:1(9Z))
PE(TXB2/18:2(9Z,12Z))
PGP(a−25:0/5−iso PGF2VI)
PS(20:2(11Z,14Z)/TXB2)
PS(PGJ2/20:0)
PG(20:2(11Z,14Z)/LTE4)
PS(20:1(11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
380_1alpha,3beta,22R−Trihydroxyergosta−5,24E−dien−26−o....
DG(10:0/0:0/LTE4)
INDOPHENOL
PE(20:0/TXB2)
PC(18:1(11Z)/PGJ2)
PS(22:2(13Z,16Z)/PGD2)
PC(16:0/PGJ2)
Carbocyclic 3−deazaadenosine
Indoximod
Serylvaline
581_2−Acetyl−1,5,6,7−tetrahydro−6−hydroxy−7−(hydroxyme....
Brassinolide
Sonchuionoside C
PS(20:3(6,8,11)−OH(5)/22:0)
PC(P−16:0/22:6(4Z,7Z,11E,13Z,15E,19Z)−2OH(10S,17))
SM(d20:1/LTE4)
PS(19:1(9Z)/22:4(7Z,10Z,13Z,16Z))
Ascorbigen
PC(15:0/22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S, 17S))
PS(20:2(11Z,14Z)/20:4(5Z,8Z,11Z,13E)+=O(15))
PC(PGE1/18:4(6Z,9Z,12Z,15Z))
473_(17E,19E,21E,23E,25E)−4,6,8,10,12,14,16,27−Octahyd....
393_PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,11E,13Z,....
Spirolide E
(20E)−Ginsenoside F4
PS(22:1(13Z)/PGE1)
PS(14:1(9Z)/16:1(9Z))
PE(14:1(9Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)−OH(4))
PI(18:0/PGF2alpha)
PA(10:0/20:4(8Z,11Z,14Z,17Z)−2OH(5S,6R))
PC(18:0/22:6(4Z,7Z,11E,13Z,15E,19Z)−2OH(10S,17))
443_PS(22:1(13Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)−2OH(7S, 1....
PE(24:1(15Z)/20:3(8Z,11Z,14Z)−2OH(5,6))
3−O−Sulfogalactosylceramide (d18:1/14:0)
314_PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:5(7Z,9Z,11E,13E,....
PC(P−16:0/5−iso PGF2VI)
PC(17:0/PGF2alpha)
PC(16:0/22:6(4Z,7Z,11E,13Z,15E,19Z)−2OH(10S,17))
PS(20:0/20:5(5Z,8Z,11Z,14Z,16E)−OH(18R))
PC(DiMe(11,3)/PGF1alpha)
SM(d20:1/22:6(4Z,7Z,10Z,12E,16Z,19Z)−OH(14))
PE(16:0/18:3(9,11,15)−OH(13))
PC(16:0/PGF1alpha)
145_PC(22:3(10Z,13Z,16Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)−2....
PC(18:2(9Z,12Z)/TXB2)
PC(18:1(11Z)/6 keto−PGF1alpha)
PS(15:0/24:1(15Z))
PS(24:0/18:3(10,12,15)−OH(9))
PC(20:3(8Z,11Z,14Z)/PGJ2)
SM(d18:2(4E,14Z)/LTE4)
PC(16:1(9Z)/18:1(12Z)−2OH(9,10))
PC(18:2(9Z,12Z)/18:1(12Z)−2OH(9,10))
差异代谢物层次聚类热图
生化变化可能会在一定程度上影响卵子质量 [20] 。本
研究中的转录组学和代谢组学分析结果也显示，选
育系 F 代陆封型马苏大麻哈鱼的卵子发生和胚胎
5
发育相关基因和代谢物较非选育系具有显著变化。
研究发现，江鳕（Lota lota）个体的绝对繁殖
力和相对繁殖力随卵径的增加呈现微增长的趋势，
表明在一定范围内，卵径较大的江鳕可能具有更高
的繁殖潜力，江鳕个体绝对繁殖力和相对繁殖力并