Page 118 - 《渔业研究》2025年第3期

第 3 期 徐静怡等： 淡水微囊藻毒素污染现状及降解研究进展 375

using blooms of Microcystis spp. in animal feeds: a com- 理研究进展 [J]. 食品科学，2020，41（5） ：290 −
prehensive review of nutritional, toxicological and mi- 298.
crobial health evaluation[J]. Science of the Total Envir- He Y, Huang X Z, Ding X W. Advances in research on
onment, 2021, 764: 142319. toxicity and mechanism of action of microcystins[J].
［25］ 吴琴. 微囊藻毒素-LR 诱发斑马鱼神经毒性的分子机 Food Science, 2020, 41(5): 290 − 298.
制研究 [D]. 武汉：华中农业大学，2019. ［34］ Chowdhury R R, Rose S, Ezan F, et al. Hepatotoxicity of
Wu Q. Molecular mechanism of neurotoxicity induced cyanotoxin microcystin-LR in human: insights into mech-
by microcystin-LR in zebrafish[D]. Wuhan: Huazhong anisms of action in the 3D culture model Hepoid-Hep-
Agricultural University, 2019. aRG[J]. Environmental Pollution, 2024, 342: 123047.
［26］ Mackintosh C, Beattie K A, Klumpp S, et al. Cyanobac- ［35］ Xu S S, Yi X P, Liu W Y, et al. A review of nephrotox-
terial microcystin-LR is a potent and specific inhibitor of icity of microcystins[J]. Toxins, 2020, 12(11): 693.
protein phosphatases 1 and 2A from both mammals and ［36］ Yao X Q, Liu Y, Yang Y, et al. Microcystin-LR-expos-
higher plants[J]. FEBS Letters, 1990, 264(2): 187 − 192. ure-induced kidney damage by inhibiting MKK6-medi-
［27］ Prieto A, Campos A, Cameán A, et al. Effects on growth ated mitophagy in mice[J]. Toxins, 2023, 15(6): 404.
and oxidative stress status of rice plants (Oryza sativa) ［37］ Ma Y, Liu H H, Du X D, et al. Advances in the toxico-
exposed to two extracts of toxin-producing Cyanobac- logy research of microcystins based on omics approa-
teria (Aphanizomenon ovalisporum and Microcystis aer- ches[J]. Environment International, 2021, 154: 106661.
uginosa)[J]. Ecotoxicology and Environmental Safety, ［38］ 杜星德，张慧珍. 微囊藻毒素-LR 致生殖细胞凋亡的
2011, 74(7): 1973 − 1980. 分子机制研究进展 [J]. 沈阳医学院学报，2020，
［28］ Chen J, Han F X, Wang F, et al. Accumulation and 22（5） ：385 − 390.
phytotoxicity of microcystin-LR in rice (Oryza sativa) Du X D, Zhang H Z. Advances in the molecular mechan-
[J]. Ecotoxicology and Environmental Safety, 2012, 76: ism of germ cell apoptosis induced by microcystin-
193 − 199. LR[J]. Journal of Shenyang Medical College, 2020,
［29］ Corbel S, Mougin C, Martin-Laurent F, et al. Evaluation 22(5): 385 − 390.
of phytotoxicity and ecotoxicity potentials of a cyanoba- ［39］ Hinojosa M G, Gutiérrez-Praena D, Prieto A I, et al.
cterial extract containing microcystins under realistic en- Neurotoxicity induced by microcystins and cylindrosper-
vironmental concentrations and in a soil-plant system[J]. mopsin: a review[J]. Science of the Total Environment,
Chemosphere, 2015, 128: 332 − 340. 2019, 668: 547 − 565.
［30］ 刘洪月. 微囊藻毒素对水稻生长、激素水平与矿质营 ［40］ Yan M H, Jin H B, Pan C, et al. Movement disorder and
养吸收的影响 [D]. 无锡：江南大学，2019. neurotoxicity induced by chronic exposure to microcy-
Liu H Y. Effects of microcystins on growth, hormone stin-LR in mice[J]. Molecular Neurobiology, 2022,
level and mineral nutrient absorption of rice (Oryza 59(9): 5516 − 5531.
sativa)[D]. Wuxi: Jiangnan University, 2019. ［41］ 周晓蝶，杨越，奉水东，等. 微囊藻毒素的肠道毒性
［31］ Wang N Y, Wang C. Effects of microcystin-LR on the 研究进展 [J]. 中国科学：生命科学，2023，53（10） ：
tissue growth and physiological responses of the aquatic 1479 − 1489.
plant Iris pseudacorus L.[J]. Aquatic Toxicology, 2018, Zhou X D, Yang Y, Feng S D, et al. Research progress
200: 197 − 205. on intestinal toxicity of microcystins[J]. Scientia Sinica
［32］ Malaissi L, Vaccarini C A, Hernández M P, et al. (Vitae), 2023, 53(10): 1479 − 1489.
[D-Leu1] MC-LR and MC-LR: a small-large difference: ［42］ 黄会，刘慧慧，李佳蔚，等. 水产品中微囊藻毒素检
significantly different effects on Phaseolus vulgaris L. 测方法及污染状况研究进展 [J]. 中国渔业质量与标
(Fabaceae) growth and phototropic response after single 准，2019，9（2） ：32 − 43.
contact during imbibition with each of these microcystin Huang H, Liu H H, Li J W, et al. Progress on study of
variants[J]. Toxins, 2020, 12(9): 585. detection methods and pollution condition of microcy-
［33］ 贺燕，黄先智，丁晓雯. 微囊藻毒素毒性及其作用机 stins in aquatic products[J]. Chinese Fishery Quality and