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(Zhongguo Yaoke Daxue Xuebao)  Volume 56
                                                                                                    August
                                                                   JOURNAL OF CHINA                 2025 04       ISSN 1000-5048
                                                   PHARMACEUTICAL UNIVERSITY                        CONTENTS





               Special Column: Nucleic Acid Sensing and Drug Discovery


               Column Commentary


               405   Research progress on nucleic acid pattern recognition mechanisms and their chemical interventions

                          ······················································································ JIA Jiaqing/LI Hui/YOU Qidong/XU Xiaoli
               416   Molecular diversity and evolutionary mechanisms of bacterial nucleic acid sensing systems:

                         a focus on the CBASS innate immune system ·········································· BIAN Wenjing/LI Mei/XIAO Yibei
               424   Opportunities and challenges for the development, delivery and immunotherapy of ASO

                          ························································································· LIAO Menggui/ZHU Chen/WANG Yajun
               432    Therapeutic development strategies for modulating GLI1-DNA interactions
                          ························································ QIAO Zhenyu/LUO Yongfu/PEI Yaoye/LI Xiangyang/LU Mengchen
               444  Application of mRNA vaccines in cancer immunotherapy ·············································· YU Jing/YANG Zhenjun

               Original Articles


               453   Synthesis of asiatic acid derivatives and determination of their anti-tumor activities

                          ········································································· CHEN Guo/LIU Liming/GU Tongtong/MENG Yanqiu
               460   Research on the drug-drug interaction between mecobalamin and ceftriaxone

                         in rats based on pharmacokinetics ················································· WANG Chengxin/ZHU Lili/CAO Lijuan
               469   PPARβ agonist ZLY16 promotes muscle regeneration and improves motor performance of mdx mice
                          ·········································································································· GUO Guangyao/LU Qian/
                                                                 FAN Shusheng/YU Qinwei/ZHANG Luyong/JIANG Zhenzhou
               478   Effects of thymopentin in promoting T-cell infiltration and inhibiting the growth of

                         subcutaneous hepatocellular carcinoma in mice ······················· YU Jiamo/ZHANG Ye/TANG Lingai/LI Xianjing
               488   Sodium propionate is superior to mixed short-chain fatty acids in alleviating colitis in mice
                         induced by Citrobacter rodentium ·································································· LI Yingying/WANG Liuyi/
                                                                        WANG Sijin/YANG Yiwen/XIN Fei/LI Li/JI Qiaorong
               498   Effect of β-adrenergic receptor blockers on the sleep architecture of mice ················ QU Jing/LIANG Yutao/HAN Lei/

                                                              XING Ye/WANG Long/LIN Zhuochao/LIU Kepeng/SHI Guangsen
               Reviews


               507   Research progress on active ingredients of traditional Chinese medicine improving metabolic
                         dysfunction-associated steatotic liver disease via regulating lipid metabolism ·········· LI Hailan/ZHU Zihan/LI Yue/
                                                                          XIAO Mengxue/ZHANG Yuanyuan/KOU Junping
               515    Research progress in chemical constituents and pharmacological activities of Inonotus obliquus
                          ·························································· CUI Jiamin/FAN Hairan/KUAI Haimin/HU Xiaolong/WANG Hao
               524   Research progress on additives regulating drug crystal morphology

                          ······································································································· REN Yifei/SU Yuan/CAI Ting
               531   Progress in the development of malaria vaccines

                          ························································································ ZHOU Ke/CHEN Zongxiang/LIU Lanjun









                                                                                           Edited by CHEN Ling
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