Page 149 - 《渔业研究》2025年第6期

840 渔 业 研 究 第 47 卷

［22］ Ming J H, Wang T, Wang T H, et al. Effects of dietary Physiology and Biochemistry, 2023, 49(5): 769 − 786.
berberine on growth performance, lipid metabolism, anti- ［23］ Liu Y, Chen Y, Tian L, et al. Dietary berberine supple-
oxidant capacity and lipometabolism-related genes expre- mentation enhances antioxidant capacity and improves
ssion of AMPK signaling pathway in juvenile black carp intestinal health in rainbow trout (Oncorhynchus mykiss)
(Mylopharyngodon piceus) fed high-fat diets[J]. Fish [J]. Fish & Shellfish Immunology, 2016, 58: 325 − 331.

Effects of berberine supplementation in feed on growth, liver biochemical

indices, and muscle nutrient composition of Micropterus salmoides

CHEN Jianchun
(Xiamen Marine and Fisheries Research Institute, Xiamen 361008, China)

Abstract: [Objective] This study aims to investigate the effects of berberine on the growth performance and
nutritional status of Micropterus salmoides, and seek solutions to mitigate the adverse impacts caused by high-
starch diets. [Methods] The study formulated five groups of experimental diets by supplementing high-starch
diets with 0 (the control group), 50, 100, 150, and 200 mg/kg of berberine, respectively. Juvenile M. salmoides
[(1.49±0.02) g per fish] were randomly divided into five groups, with three replicate glass aquaria per group
and 50 fish per aquarium. The experimental fish were fed the five diets separately for eight weeks, with two
feedings per day. [Results] Compared with the control group, the group of berberine at concentrations of
50−100 mg/kg significantly improved the weight gain rate (WGR), specific growth rate (SGR), total antioxid-
ant capacity (T-AOC) in the liver, activities of liver superoxide dismutase (SOD) and catalase (AT), glutathione
(GSH) content in the liver, and muscle protein content of M. salmoides. Additionally, it reduced the feed con-
version ratio, malondialdehyde (MDA) content in the liver, and muscle fat content. However, the group of ber-
berine at concentrations of 150−200 mg/kg did not further enhance the growth performance and liver antioxid-
ant capacity of the fish. [Conclusion] Therefore, it can be concluded that berberine can alleviate the reduction
in growth performance and liver oxidative stress induced by high-starch diets in juvenile M. salmoides, thereby
improving their nutritional status.
Key words: Micropterus salmoides; berberine; growth; antioxidant capacity