Page 107 - 《运动与健康科学》(英文)2024年第2期

TaggedAPTARAFigure TaggedAPTARAEndSleep, physical activity, and type 2 diabetes 229

Fig. 4. Joint associations of accelerometer-measured sleep duration and total volume of PA, MVPA, or LPA with incident type 2 diabetes. Total volume of PA was
categorized by median (low: 27.23mg; high: >27.23mg). LPA was categorized by median (low: 1839.69 min/week; high: >1839.69 min/week). MVPA was
dichotomized based on the WHO guideline (150 min of MPA, 75 min of VPA, or an equivalent combination of MPA and VPA per week). The multivariable
Cox model was adjusted for age, sex, ethnicity, season of accelerometer wearing, recruitment center, Townsend Deprivation Index, education level, smoking
status, alcohol consumption, healthy diet score, obesity status, TV watching time, grip strength, HbA1c, hypertension, high cholesterol, depression, and family
history of diabetes. 95%CI = 95% confidence interval; HbA1c = glycated hemoglobin; LPA = light-intensity physical activity; MPA = moderate physical activity;
MVPA = moderate-to-vigorous physical activity; PA = physical activity; VPA = vigorous physical activity; WHO = World Health Organization.TaggedAPTARAEnd

TaggedAPTARAH24.1. Independent association of accelerometer-measured TaggedAPTARAPThe current results replicate solid findings regarding the
protective effect of MVPA against type 2 diabetes risk and they
sleep duration and PA with incident type 2 diabetesTaggedAPTARAEnd
corroborate the consensus on adhering to the WHO recommenda-
TaggedAPTARAPUsing accelerometer-measured data, the current findings repli-
tion of 150 min of MPA or 75 min of VPA per week to prevent
cated the widely recognized association between short sleep dura- 24
type 2 diabetes. Interestingly, the current study discovered a
tion and increased risk of type 2 diabetes based on self-reports,
weaker but significant inverse prospective association between
with the strength of this association similar to that of existing LPA and incident type 2 diabetes. While MVPA has been well
6
6
findings. Meanwhile, in contrast to existing findings, this study
recognized for its significance in reducing type 2 diabetes risk,
found no excessive risk of type 2 diabetes associated with long
the effect of LPA is scarcely known because of the insensitivity
sleep duration. Similar null associations of long sleep have been 11
of self-report measurements adopted by most existing studies.
observed among several cardiometabolic outcomes, using objec- To the best of our knowledge, this is the first study to find direct
tive sleep measurements 16,30 and genetically predicted long support for the protective role of LPA in the development of type
sleep. 31 One possible explanation for the inconsistency between
2 diabetes among the general population. Both MVPA reaching
objective and subjective measurements is that self-reported long
the WHO-recommended level and LPA 1840 min/week are
sleep could have reflected an overestimation of sleep, such as
associated with a lower risk of type 2 diabetes.TaggedAPTARAEnd
including excessive time in bed, a fragmented sleep process, or a
sedentary lifestyle. 32 All these factors could contribute to the
TaggedAPTARAH24.2. Joint association of accelerometer-measured sleep
increased risk of type 2 diabetes in self-reported studies. Indeed,
poorer sleep quality and longer sedentary time are associated duration and PA with incident type 2 diabetesTaggedAPTARAEnd
with a higher risk of type 2 diabetes. 33,34 This suggests that objec- TaggedAPTARAPTo our knowledge, this is also the first study to systemati-
tive sleep measurements should be involved in the screening and cally examine the joint association of objectively measured
sleep duration and PA with the onset of type 2 diabetes from a
prevention of type 2 diabetes.TaggedAPTARAEnd