Page 9 - 《运动与健康科学》(英文)2024年第2期

TaggedAPTARAEndExerkines and exercise training 131
TaggedAPTARAPThese examples illustrate that an exerkine may exhibit TaggedAPTARAH1Concluding remarksTaggedAPTARAEnd
discordant responses to acute exercise compared to exercise 1
TaggedAPTARAPThis recent systematic review by Garc ıa-Hermoso et al.
training, with the discordance being characterized by aspects
provides an important contribution to an important aspect of the
such as the direction of change in concentration, the cell- or
ever-expanding field of exerkine research. The findings reported
tissue-specific source of the exerkine, and the metabolic conse-
provide thought-provoking insights into how exerkines are pre-
quence of exerkine action. Another important implication is
sently understood to respond to exercise training, and we intend
that characterisation of the acute exerkine response cannot be
our comments to provide useful considerations for planning and
used to infer the response to exercise training, and especially
interpretation of future experiments in this field.TaggedAPTARAEnd
if there are several cell/tissue sources of that exerkine, and
several possible mechanisms of action. This point is salient
TaggedAPTARAH1AcknowledgmentsTaggedAPTARAEnd
given that several recent studies report a comprehensive char-
acterisation of the exerkine response to acute exercise, 12,13 yet TaggedAPTARAPThis work was supported by funding from The Irish
the implications for metabolic health and adaptations to Research Council through both the Government of Ireland
exercise training for many candidate exerkines remain to be Postgraduate Scholarship Programme to IAJD and BE (Grant
No. GOIPG/2020/162). The Irish Research Council is an asso-
described.TaggedAPTARAEnd
ciated agency of the Department of Education and Skills and
TaggedAPTARAH1The residual influence of the most recent acute exercise boutTaggedAPTARAEnd
operates under the aegis of the Higher Education Authority of
TaggedAPTARAPAcute exercise bouts produce short-term improvements Ireland.TaggedAPTARAEnd
in markers of cardiovascular and metabolic health, such as
reduced blood pressure and circulating triglycerides, and TaggedAPTARAH1Authors’ contributionsTaggedAPTARAEnd
increased insulin sensitivity. 9 These benefits can persist
for periods of »1648 h, 1417 but many benefits are not TaggedAPTARAPIAJD contributed to the conceptualization, formal analysis,
augmented or attenuated with a period of exercise training. 9,18 and writing of the original draft; BE contributed to the concep-
tualization, writing (review and editing), and supervision, as
These observations demonstrate that acute exercise is capable
well as funding acquisition. Both authors have read and
of conveying discrete benefits that are independent from
approved the final version of the manuscript, and agree with
responses or adaptations to exercise training, an effect previ-
ously termed as “last bout effects”. 18 From a methodological the order of presentation of the authors.TaggedAPTARAEnd
perspective, when investigating the effects of exercise training
specifically, the presence of protracted residual influences of a TaggedAPTARAH1Competing interestsTaggedAPTARAEnd
recent acute exercise bout may be a confounding factor in TaggedAPTARAPBoth authors declare that they have no competing interests.TaggedAPTARAEnd
studies where the timing of the post-training blood sample has
not accounted for this phenomenon. An example would be
TaggedAPTARAH1ReferencesTaggedAPTARAEnd
when post-training blood samples are taken <24 h after the
last exercise bout of the training intervention. In a recent TaggedAPTARAListItem TaggedAPTARAListLabel1TaggedAPTARAEnd. Garc ıa-Hermoso A, Ram ırez-V elez R, D ıez J, Gonz alez A, Izquierdo M.
Exercise training-induced changes in exerkine concentrations may be rele-
multi-omic investigation, most candidate exerkines identified
vant to the metabolic control of type 2 diabetes mellitus patients: A
to change in response to acute exercise trended back towards systematic review and meta-analysis of randomized controlled trials.
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continue to increase at 1 h after exercise. 12 Few studies have TaggedAPTARAListItem TaggedAPTARAListLabel2TaggedAPTARAEnd. Chow LS, Gerszten RE, Taylor JM, et al. Exerkines in health, resilience
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3
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