Page 24 - 《中国医疗器械杂志》2025年第6期

Chinese Journal of Medical Instrumentation 2025年 第49卷 第6期

研 究 与 论 著

文章编号：1671-7104(2025)06-0610-08

加样针设计方法及针粗糙度对生化分析仪性能影响的研究

【作 者】 杨超群，潘洋，赵鹏
安图实验仪器（郑州）有限公司，郑州市，450016
【摘 要】 针对高速生化分析仪加样精度差、试剂实验结果不稳定和携带污染超标的难题，本研究以A公司B项目为例
系统探究加样针结构设计方法。从精确调整针芯尺寸、运用变径结构、严格把控针芯内外壁粗糙度等维度
进行分析设计，并通过雷诺数计算和ANSYS仿真保证流体状态和针的强度，成功研发适配高速仪器的加样
针结构。对不同厂商加样针进行粗糙度测量，并开展小体积定量、试剂实验及携带污染等测试，根据不同
粗糙度对应的结果进行深入分析。研究表明，针芯尺寸、变径结构对加样针的加样时流体状态和针的强度
都产生较大影响，优化后加样针结构显著提升加样稳定性和精度，增强清洗效果，降低针挂液量；同时针
芯内外壁粗糙度等参数的科学设定，又是决定生化分析仪定量准确性、试剂实验可靠性和携带污染水平等
整机性能的核心要素。
【关 键 词】 加样针；结构设计；加样精度；内外壁粗糙度；整机性能
【中图分类号】 TH776; R318.6
【文献标志码】 A doi: 10.12455/j.issn.1671-7104.250204
Research on Influence of Sampling Needle Design Methods and Needle
Roughness on Performance of Biochemical Analyzers
【 Authors 】 YANG Chaoqun, PAN Yang, ZHAO Peng
Autobio Labtec Instruments Co., Ltd., Zhengzhou, 450016
【 Abstract 】 Aiming at the challenges of poor sampling accuracy, unstable reagent test results, and excessive
carryover contamination in high-speed biochemical analyzers, this study systematically investigated the
structural design methodology of sampling needles, using Company A's Project B as a case study. The
design focused on precise adjustment of needle core dimensions, the application of variable-diameter
structures, and strict control of the inner and outer wall roughness of the needle core. Reynolds number
calculations and ANSYS simulations were employed to ensure optimal fluid dynamics and needle
strength, resulting in the successful development of a sampling needle structure compatible with high-
speed instruments. Roughness measurements were conducted on sampling needles from different
manufacturers, followed by tests on small-volume quantification, reagent performance, and carryover
contamination. The results were analyzed in depth based on varying roughness levels. The research
demonstrates that needle core dimensions and variable-diameter structures significantly influence fluid
dynamics during sampling and needle strength. The optimized needle structure notably improves
sampling stability and precision, enhances cleaning efficiency, and reduces residual liquid adhesion.
Furthermore, the scientific setting of parameters such as inner and outer wall roughness is identified as a
critical factor determining the overall performance of biochemical analyzers, including quantification
accuracy, reagent test reliability, and carryover contamination levels.
【Key words】 sampling needle, structural design, sampling accuracy, inner and outer wall roughness, instrument
performance

0 引言 度日益提升，疾病的精准治疗愈发依赖医疗检测
设备 [1-3] 。其检测结果能为医师的诊断提供不可或
随着生活节奏的加快，人们对健康的重视程 缺的依据，因此，确保生化检测设备检测结果的

可靠性和准确性，是实现疾病有效诊断与治疗的
收稿日期：2025-03-28
[4]
作者简介：杨超群，E-mail: yangchaoqun@autobio.com.cn 基础 。为保障检测仪检测结果的精确性与稳定

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